| Home Team | Home Pitcher | Visiting Team | Visiting Pitcher | Date/Time | Notes |
|---|---|---|---|---|---|
| Lexington (20-9-1) | Blythewood (24-6) | Johnny Collins | 05/22 06:00 PM | 5A D1 Upper State Finals - Game 2 | |
| Stratford (22-5-2) | James Island (27-3) | 05/22 06:30 PM | 5A D1 Lower State Finals - Game 2 | ||
| Catawba Ridge (21-8-1) | Indian Land (25-5) | 05/22 06:00 PM | 5A D2 Upper State Final - Game 2 | ||
| Berkeley (19-10) | West Florence (22-5) | 05/22 06:00 PM | 5A D2 Lower State Final - Game 2 | ||
| Daniel (23-10) | Seneca (24-6) | 05/22 06:30 PM | 4A Upper State Final - Game 2 | ||
| South Florence (20-11) | Landon Hill | Airport (24-6) | Hunter Epps (8-3-3, 1.33) | 05/22 06:30 PM | 4A Lower State Final - Game 2 |
| Chapman (21-8) | Southside Christian (29-2-1) | Carson Boleman | 05/21 05:00 PM | 3A Upper State Final | |
| Oceanside Collegiate (26-5) | Charlie Becker | Hanahan (20-9-2) | Riley Ballard | 05/21 05:00 PM | 3A Lower State Finals |
| Batesburg-Leesville (21-5-1) | Carter Bouknight | Strom Thurmond | Bryson Swearingen (5-2) | 05/21 05:00 PM | 2A Upper State Final |
| Philip Simmons | Pierce Mullen (5-2) | East Clarendon (25-7) | Foster Matthews (11-1) | 05/21 05:00 PM | 2A Lower State Final |
| Ware Shoals | McBee | 05/21 12:00 AM | 1A Upper State Final | ||
| Latta | Lake View | Kason Herlong (6-0) | 05/21 06:00 PM | 1A Lower State Final |
